A two-site phosphorylation cycle, where phosphorylation is catalyzed by the same kinase at both sites and dephosphorylation is catalyzed by the same phosphatase at both sites [Feliu, Wiuf].
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In the motif Two-site Modification G, the symbols used in the chemical reactions have the following meaning:
S_i and P_i are substrates with i = 0, 1, 2 phosphorylated sites, E is a kinase and F is a phosphotase, X and Y are the intermediate complexes formed by the enzymes E and F, respectively.
To rename species, use substitute(ReactionNetwork,List).
The object twoSiteModificationG is a method function.
The source of this document is in /build/reproducible-path/macaulay2-1.25.06+ds/M2/Macaulay2/packages/ReactionNetworks/DocReactionNetworks.m2:358:0.